Interesting! Did they mention vNUMA at all? It wasn't available until virtual hardware v8, so I'm curious if they've included it in their testing. The jist is that it creates a virtual NUMA topology that aligns with the host's physical NUMA topology. The reason I asked about 8 CPUs is that vNUMA gets enabled by default once you cross that threshold. If all of the hosts in your cluster have a consistent NUMA topology, this can be a pretty effective alternative to CPU/memory affinity in many cases, without the DRS/vMotion restrictions.
Anyway, good luck! I can appreciate the jack of all trades position you're in. It's certainly possible they have a valid use case.