since you have 4 nics i would suggest the following design to offer redundancy.
vmotion, management network and VM network in same switch "vSwitch0" with uplinks vmnic0 and vmnic3.
And vSwitch1 with up links vmnic4 and vmnic5 dedicated for iSCSI.
since you have 4 nics i would suggest the following design to offer redundancy.
vmotion, management network and VM network in same switch "vSwitch0" with uplinks vmnic0 and vmnic3.
And vSwitch1 with up links vmnic4 and vmnic5 dedicated for iSCSI.